Application of Neutrophil-lymphocyte Ratio in the Diagnosis of Influenza in Preschool Children
Yuan Xiaohong,
Li Peng,
Li Yuwei
Issue:
Volume 7, Issue 6, November 2019
Pages:
100-103
Received:
13 November 2019
Accepted:
27 November 2019
Published:
6 December 2019
Abstract: Objective: To analyze the prevalence of influenza A/B in preschool children and neutrophils to lymphocytes ratio (NLR) of influenza A/B positive patients and patients with influenza-like illness, in order to provide more ideas and basis for the prevention, diagnosis and treatment of influenza-like illness. Methods: Children who were not more than 6 years old, and screened for antigen of influenza viruses in the Second Affiliated Hospital of Xi'an Jiaotong University, were enrolled in this study from November 2017 to February 2018. The venous blood or finger tip blood of the participants were collected for blood routine test. SPSS 19.0 software was used to analyze data. Results: Totally 99 (26.19%) cases with positive influenza A were observed in 378 children with influenza-like illness, 44 (11.64%) cases with positive influenza B, and the 225 cases were not infected. There was significant difference on the value of NLR between patients with influenza A infection and children without infection (P<0.05). When NLR was 0.42, the sensitivity for the prognosis was 86.1%, the specificity was 93.2%, and the area under curve (AUC) was 0.594. Conclusion: NLR has certain clinical value for the diagnosis of Influenza influenza, and can be helpful to diagnose influenza A virus infection by influenza virus antigen screening.
Abstract: Objective: To analyze the prevalence of influenza A/B in preschool children and neutrophils to lymphocytes ratio (NLR) of influenza A/B positive patients and patients with influenza-like illness, in order to provide more ideas and basis for the prevention, diagnosis and treatment of influenza-like illness. Methods: Children who were not more than 6...
Show More
Prevalence of Group b Streptococcus, Its Associated Factors and Antimicrobial Susceptibility Pattern Among Pregnant Women Attending Antenatal Care at Arbaminch Hospital, South Ethiopia
Shimelis Shiferawu,
Mekidm Mekonen,
Daniel Baza,
Temesgen Lera
Issue:
Volume 7, Issue 6, November 2019
Pages:
104-115
Received:
23 September 2019
Accepted:
30 October 2019
Published:
25 December 2019
Abstract: Background: Group B Streptococcus colonization of the gastrointestinal and genital tracts of pregnant women usually remains asymptomatic; even if it is the critical determinant of infection in neonates and young infants. It causes early and late onset of invasive Group B Streptococcus (GBS) disease manifesting as septicemia, meningitis and pneumonia. Now it is recognized as an important cause of maternal and neonatal morbidity and mortality in many parts of the world including Ethiopia where the magnitude of the problem has been little studied. Objectives: The aim of this study was to determine the prevalence of GBS colonization, to identify associated risk factors and antimicrobial susceptibility pattern of GBS isolates among pregnant women attending antenatal care at Arbaminch General Hospital, Arbaminch, Ethiopia. Methods: A cross sectional study was conducted from March - July, 2016 among 281 pregnant women on their antenatal care (ANC) visit at Arbaminch General Hospital (AGH). Consented participants’ information was collected using structured questionnaire. Recto-vaginal swab samples were collected by consecutive sampling technique and inoculated directly onto 5% sheep blood agar (SBA) for isolation of GBS. Antimicrobial susceptibility testing was performed according to the clinical and laboratory standard institute (CLSI) guideline, 2014 by disk diffusion method. Data was coded and entered into EPidata version 3.1 and analyzed by SPSS version 21.0. Bivariate and Multivariate logistic regression analysis were used to ascertain the association between explanatory and outcome variable considering p-value <0.05. Result: The colonization rate of GBS among pregnant mothers was 8.5%. The overall recto-vaginal GBS colonization in this study was not significantly associated with any of socio-demographic and obstetric factors. All of the GBS isolates were susceptible to penicillin, ampicillin and vancomycin. Resistance to ciprofloxacin, ceftriaxone, clindamycin, erythromycin, chloramphenicol and gentamycin was found to be 37.5%, 29.2%, 29.2%, 20.8%, 8.3%, and 4.2%, respectively. From a total of twenty four GBS isolates, two showed multidrug resistance. Conclusion and recommendation: This study found that GBS colonization rate was rationally high and most isolates were resistant to the commonly used antibiotics.
Abstract: Background: Group B Streptococcus colonization of the gastrointestinal and genital tracts of pregnant women usually remains asymptomatic; even if it is the critical determinant of infection in neonates and young infants. It causes early and late onset of invasive Group B Streptococcus (GBS) disease manifesting as septicemia, meningitis and pneumoni...
Show More
