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The Rate of Anti-Chlamydia Pneumoniae IgG and IgA Antibodies Among Patients With Coronary Heart Diseases in Diyala Province, Iraq
Abbas Abood Al-Duliami,
Asmaa Haseeb Hwaid,
Fatin Ali Al-Chalabi
Issue:
Volume 3, Issue 3, May 2015
Pages:
121-124
Received:
25 March 2015
Accepted:
7 April 2015
Published:
17 April 2015
Abstract: Background: Chlamydia pneumoniae is found worldwide, it causes acute respiratory infection, especially atypical pneumonia. High prevalence of past infection with Ch. pneumoniae have been found in developing countries that may has a role in pathogenesis of coronary heart disease. Objective: The present study was sought todetermined the rate of anti- Ch. pneumoniae IgG and IgA antibodies among patients with coronary heart diseases in Diyala province, Iraq. Material and Methods: This study was conducted during the period from November/ 2013 to December/ 2014. 91 Participants were included; 45 patients with coronary heart disease (myocardial infarction, angina, and atherosclerosis) who were chosen according to clinical criteria and 46 apparently healthy individuals as control group. The mean age of the patients was (59.20 ± 11.45) years with an age rang (40-90) years, and for the controls, and the mean age was (35.43 ± 8.67) years with an age rang (32-86) years. Detection of anti- Ch. pneumoniae IgG and IgA antibodies was done by Enzyme – Linked Immunosorbant Assay (Nova Tec immundiagnostica GmbH, Germany). Results: The present results study show that the positivity rate of anti-Ch. pneumoniae IgG antibodies was significantly higher among patients compared to controls (66.67%vs54.35%, P ≤ 0.05). While, the seroprevalence of anti- Ch. pneumoniae IgA antibodies among patients and controls was 24.44%and 13.04% respectively, this results showed that there is a statistically significant association between Chlamydia pneumoniae and CHD, P ≤ 0.05. Conclusion: The presence of anti-Ch. pneumoniae IgG and IgA are significantly associated with CHD patients in Diyala province.
Abstract: Background: Chlamydia pneumoniae is found worldwide, it causes acute respiratory infection, especially atypical pneumonia. High prevalence of past infection with Ch. pneumoniae have been found in developing countries that may has a role in pathogenesis of coronary heart disease. Objective: The present study was sought todetermined the rate of anti-...
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A Malaria Outbreak in Ameya Woreda, South-West Shoa, Oromia, Ethiopia, 2012: Weaknesses in Disease Control, Important Risk Factors
Gemechu Beffa Defi,
Ayele Belachew,
Adamu Addissie,
Zegeye Hailemariam
Issue:
Volume 3, Issue 3, May 2015
Pages:
125-129
Received:
31 March 2015
Accepted:
7 April 2015
Published:
18 April 2015
Abstract: Malaria is endemic in Ethiopia but regional health bureaus have set goals for elimination of the disease through the implementation of aggressive malaria control and eradication measures. In May 2012 an increased number of malaria cases were reported from Ameyaworeda, South-West Shoa, Ethiopia, which previously had been targeted for elimination. We investigated to understand associated risk factors and propose control measures.We reviewed data from health post records from 2008 to 2012 to identify the baseline incidence of malaria for Ameya. We defined a confirmed case as a patient with malaria confirmed by microscopy or a rapid diagnostic test. From May 18 to June 10, 2012 we randomly selected 144 newly diagnosed malaria patients and compared with 144 community matched controls. Multivariate analysis was performed using Epi Info version 3.5.3. We also assessed environmental conditions.The baseline incidence rate for malaria prior to the outbreak was 1/1000 population. Between March 2012 and May 2012 4768 cases were reported with a peak during May [Incidence: 37per 1,000 and no fatalities]. Using multivariate analysis, cases were found to be less likely to use ITN’s [OR: 0.09; 95%CI 0.05-0.16] and less likely to spray their houses [OR: 0.45; 95%CI 0.21-0.97] when compared with controls. Environmental assessment revealed the presence of stagnant water, which was favorable for mosquito breeding. We identified several factors that contributed to the outbreak, which included a low utilization of ITN’s, ideal conditions for vector breeding, a weak case detection system. We recommended and helped implement a community awareness program on the utilization of ITN’s, environmental management and focal indoor residual spray (IRS).
Abstract: Malaria is endemic in Ethiopia but regional health bureaus have set goals for elimination of the disease through the implementation of aggressive malaria control and eradication measures. In May 2012 an increased number of malaria cases were reported from Ameyaworeda, South-West Shoa, Ethiopia, which previously had been targeted for elimination. We...
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Factors Determining Health Institutional Delivery Among Pregnant Women Living in Agarfa Town of Bale Zone, Oromia, South East Ethiopia
Tomas Benti Tefera,
Kemal Ahmed Kuti
Issue:
Volume 3, Issue 3, May 2015
Pages:
130-134
Received:
17 March 2015
Accepted:
29 March 2015
Published:
18 April 2015
Abstract: Background: About 800 women die from pregnancy- or childbirth-related complications around the world every day. In 2013, 289 000 women died during and following pregnancy and childbirth. Almost all of these deaths occurred in low-resource settings. According to the latest estimate maternal mortality ratio in Ethiopia was 420/100,000 live births in 2013 which is still high. Severe bleeding, infection, high blood pressure during pregnancy and complication from delivery, accounts for nearly 75% of these deaths. Even though ANC follows up, Institutional delivery and skilled birth attendance is one of the key and proven interventions to reduce maternal death most deliveries, in Ethiopia, skilled birth attendance and birth in a health facility is very low. So this study aimed to assess Factors determining Health institutional delivery among pregnant women living in Agarfa woreda of Bale Zone, Southeast Ethiopia. Methods: Community based cross sectional study was conducted in Agarfa Town from January -March, 2012 on one hundred fifty six pregnant women in the town. Systematic sampling was used to get the respondents after sampling frame including lists of households having pregnant women was prepared. Data were analyzed using SPSS version 15.0. Binary and multivariable logistic regression analyses were carried out to identify factors associated with institutional delivery service. Statistical significance was considered at p < 0.05. Results: The response rate was 98.7% (n=156). The proportion of pregnant women who had given birth at health institution were 49(31.4%), of 118 who had followed ANC for recent pregnancy, only 27(22.9%) were gave birth at health institution. Factors associated with health institution delivery were the number of pregnancies (three and above) and difficulty labour. However, difficulty labour/prolonged was remained a significant predictor of institutional delivery. Conclusions: Despite the high level of ANC attendance among the pregnant women in the study area, the study has revealed that mothers were not considerably utilizing institutional delivery and skilled birth attendants and majority of them still choose Home delivery. Pregnant women wait till they experience difficult labour to seek health institutional delivery.
Abstract: Background: About 800 women die from pregnancy- or childbirth-related complications around the world every day. In 2013, 289 000 women died during and following pregnancy and childbirth. Almost all of these deaths occurred in low-resource settings. According to the latest estimate maternal mortality ratio in Ethiopia was 420/100,000 live births in ...
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Serum Mannose Binding Lectin Levels in Early Onset Neonatal Sepsis
Andi Risko Amalia,
Ema Alasiry,
Dasril Daud
Issue:
Volume 3, Issue 3, May 2015
Pages:
135-139
Received:
9 April 2015
Accepted:
14 April 2015
Published:
24 April 2015
Abstract: Introduction: Early Onset Neonatal Sepsis (EONS) is still the most cause of neonatal morbidity and mortality. The diagnosis is difficult to establish because of nonspecific clinical features and laboratory findings. Mannose binding lectin (MBL) is one of the acute phase proteins that can show progressing infection process. Objective: To determine the serum MBL levels of neonates with EONS and not EONS. Methods: This study was conducted as a cross sectional study from September to November 2014. The population included 92 neonates baby whose mother has risk factors of sepsis and admitted to Dr. Wahidin Sudirohusodo Hospital and joined hospital. The subjects were divided into two groups, EONS and Not EONS group based on clinical features and laboratory findings. The MBL serum level was measured on each group. Results: Statistical analyses showed median value of serum MBL of EONS group (0.88 μg/mL) was significant lower compare with Not EONS group (0.93 μg/mL), with p= 0.00 (p<0.05). The cutoff point of ≤0.93 µg/mL is the best levels to distinguish between EONS and Not EONS (p=0.01, sensitivity 76%, specificity 56%, positive predictive value 60%, negative predictive value 67%, COR 3.182, 95%CI 1.306-7.752). Conclusion: MBL serum levels on EONS group were lower than Not EONS group.
Abstract: Introduction: Early Onset Neonatal Sepsis (EONS) is still the most cause of neonatal morbidity and mortality. The diagnosis is difficult to establish because of nonspecific clinical features and laboratory findings. Mannose binding lectin (MBL) is one of the acute phase proteins that can show progressing infection process. Objective: To determine t...
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Anatomical Variants in Frontal Recess Region and their Impact on Frontal Sinus Surgery in Chronic Sinusitis
Omer Abd El-Moneim El-Banhawy,
Adel Tharwat Atalla,
Mohamed Ramadan El-Kholy,
Ahmed Abd El-Halim Mohammed,
Ahmed El-Mohamedy El-Neily
Issue:
Volume 3, Issue 3, May 2015
Pages:
140-145
Received:
3 April 2015
Accepted:
14 April 2015
Published:
27 April 2015
Abstract: Objective: To study the prevalence of anatomical variants in frontal recess region and their impact on frontal sinus surgery. Setting: University referral center. Patients and Methods: This was a clinical trial prospective study approved by Menoufia University research ethics board (REB) and included 50 Egyptian patients selected from the ENT department of Menoufia University between June 2011 to November 2014, who were suffering from chronic frontal sinusitis. Preoperative CT with coronal, axial and sagittal cuts were examined to show anatomical variants. Frontalsinusotomy was doneendoscopically and surgicall easiness was evaluated. Results: Increased aggernasi cell size was associated with increased operative easiness. Increase danteroposteri or diameter of frontal sinus ostium was associated with increased operative easiness.Type3frontoethmoidal air cell and interfrontal sinusseptal cells were more difficult in surgery than other frontoethmoidal air cells. Operativeeasiness correlated with different types of uncinate process superior attachment. Conclusions: Preoperative meticulous study of CT is very important for decision making in endoscopic frontal sinus surgery. Each anatomical variant in frontal recess area can be a predictor for operative easiness.
Abstract: Objective: To study the prevalence of anatomical variants in frontal recess region and their impact on frontal sinus surgery. Setting: University referral center. Patients and Methods: This was a clinical trial prospective study approved by Menoufia University research ethics board (REB) and included 50 Egyptian patients selected from the ENT depar...
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Prognostic Factor of Ureum and Creatinine Serum of Acute Post Streptococcal Glomerulonephritis in Children
Ahmad Hadiwijaya,
Husein Albar,
Syarifuddin Rauf,
Dasril Daud
Issue:
Volume 3, Issue 3, May 2015
Pages:
151-155
Received:
8 April 2015
Accepted:
18 April 2015
Published:
29 April 2015
Abstract: Introduction: Acute post streptococcal glomerulonephritis is one of the commonest causes of glomerular disease in developing countries. Ureum and creatinine examination not only can be used to support the diagnosis but also to identify and detect early organs disturbances and predict the patient prognosis. Objective: This study aims to observe the ureum and creatinine serum level in APSGN children and its relationship with the outcomes. Methods: A retrospective cohort design regarding the prognostic value of serum ureum and creatinine levels for APSGN children outcomes. The data was collected from medical records of APSGN children treated at Dr. Wahidin Sudirohusodo Hospital Makassar from 2009-2013. Results: There is no significant correlation between the outcome and sex (p=0.961), nutritional status (p=1.000), and age (p=0.108). There is a significant difference both in early ureum levels to outcome with p=0.003 and in early creatinine levels to outcome with p=0.020. There is tendency to decreased levels of ureum and creatinine serum of survival group (p=0.000) while hospitalization and trend of increased or stagnan levels of ureum and creatinine serum of non survival group while hospitalization. Multivariate analyses indicated that serum ureum levels <119 mg/dl is an independent prognostic factor for APSGN outcomes in children with p=0.032, OR 1.021, and CI 95% 1.002-1.041. Conclusion: It seems that serum ureum is an independent prognostic factor for APSGN, where serum ureum levels <119 mg/dl and creatinine levels <1.3 mg/dl have a good prognosis. Out of the 95 patients as sampled, there were 90 (94.7%) cured, and 5 (5.2%) patients died.
Abstract: Introduction: Acute post streptococcal glomerulonephritis is one of the commonest causes of glomerular disease in developing countries. Ureum and creatinine examination not only can be used to support the diagnosis but also to identify and detect early organs disturbances and predict the patient prognosis. Objective: This study aims to observe the ...
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Relationship Between Seizures in Children with Maternal Anxious Levels at Pediatrics Intensive Care Unit
Mahirina Marjani,
Martira Maddeppungeng,
Idham Jaya Ganda,
Dasril Daud
Issue:
Volume 3, Issue 3, May 2015
Pages:
156-160
Received:
16 April 2015
Accepted:
22 April 2015
Published:
6 May 2015
Abstract: Introduction: Seizure is an emergency condition that makes mother or the care taker being anxious. The anxious of parents frequently denied where as psychological problems both acute and chronic could be happened intervention as a holistic approach to the patient and her family. Objective: To analize the correlation between seizure in children hospitalization in Pediatrics Intensive Care Unit (PICU) with the maternal anxious levels. Methods: A cross-sectional study was done and the data were collected from the 29-day-old to 18 years children treated in PICU of Dr. Wahidin Sudirohusodo Hospital, Makassar from April through September 2014. Total of samples comprised 133 children were devided into two groups: 58 children in the seizure group and 75 other in the not seizure group. The maternals anxious levels are based on the HARS (Hamilton anxious rating scale) score. Results: The study revealed there is a significant correlation between the seizure in children with maternal anxious levels as shown by the Odds Ratio (OR) value of 6.286 CI95% = 2.912 – 13.569 with p value of 0.000 (p <0.01), and the mean, median, maximum and minimum values of HARS score were higher in seizure group: the values being 31.5: 26.02, 30.5: 26, and 20–50: 18–24 respectively with p= 0.000 (p<0.01). Conclusion: Severe anxious frequency evidences in maternals with children who had seizure were higher than in children without seizure, either of the HARS score of maternals.
Abstract: Introduction: Seizure is an emergency condition that makes mother or the care taker being anxious. The anxious of parents frequently denied where as psychological problems both acute and chronic could be happened intervention as a holistic approach to the patient and her family. Objective: To analize the correlation between seizure in children hosp...
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Incidence and Clinical Characteristics of Congenital Heart Disease among Neonates in Neonatal Intensive Care Unit
Ufuk Kursat Korkmaz,
Esra Akyuz Ozkan,
Ayse Neslin Akkoca,
Ebru Sivaslioglu
Issue:
Volume 3, Issue 3, May 2015
Pages:
161-165
Received:
14 April 2015
Accepted:
29 April 2015
Published:
11 May 2015
Abstract: Background: Congenital heart diseases affect a large number of newborns and account for a high proportion of infant mortality worldwide. There are regional differences in the prevalence and distribution pattern of congenital heart diseases. We aimed to evaluate the relative frequencies, risk factors and diagnostic clues of congenital heart disease in newborns at our neonatal intensive care unit. Materials and methods: Among 326 cases admitted to the Abant Izzet Baysal University Neonatal Intensive Care Unit between February 2013 - September 2014, thirty-five newborns with congenital heart disease were evaluated, retrospectively. Data was collected on a predesigned proforma containing information regarding gender, gestational age and weight at birth, family history, and associated malformations. Results: The prevalence of congenital heart disease was 10.7%. The most common cause for cardiology consultation was cardiac murmur (85.5%). The relative percentage of acyanotic and cyanotic heart defects were 91.6% and 8.4%, respectively. The most frequent acyanotic defect was ventricular septal defect with a prevalence of 22.8%. Maternal diabetes mellitus and Down syndrome were observed in 17.1% and 2.8% of cases, respectively. Conclusion: The prevalence of congenital heart disease in newborns at the neonatal intensive care unit was higher than that in all live births and most common defect was muscular VSD. The most frequent diagnostic clue was cardiac murmur.
Abstract: Background: Congenital heart diseases affect a large number of newborns and account for a high proportion of infant mortality worldwide. There are regional differences in the prevalence and distribution pattern of congenital heart diseases. We aimed to evaluate the relative frequencies, risk factors and diagnostic clues of congenital heart disease ...
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Effect of Low-Intensity Pulsed Ultrasound on Quality of Life of Knee Osteoarthritis
Joudy Gessal,
Irawan Yusuf,
Ilhamjaya Patellongi,
Gatot Lawrence
Issue:
Volume 3, Issue 3, May 2015
Pages:
166-169
Received:
21 December 2014
Accepted:
24 April 2015
Published:
12 May 2015
Abstract: Background: Knee osteoarthritis (OA) is a common disease worldwide and causes disability in elderly. Recent studies showed that therapeutic ultrasound (US) can reduced pain in various musculoskeletal disorders. Objective: To determined the effect of low-intensity pulsed US on quality of life and reduction of pain in grade 1 to 3 knee OA. Material and methods: We conducted a randomized control trial before and after therapy in 61 knee OA patients. We applied 12 sessions of low-intensity pulsed US, 20 minutes each, with frequency 1 MHz, and intensity of 0.2 W/cm2, duty cycle of 20% to 28 patients. Thirty three patients without therapy were categorized as control group. Reduction of pain by a visual analog scale and Quality of life by The Western Ontario and McMaster Universities (WOMAC) questionnaire, were obtained before and after 12 sessions. We used the Wilcoxon test to compare the median and the Mann-Whitney U test for the difference between groups with a p value of 0.05 was considering as significant. Results: We observed a reduction of pain in therapy group (VAS before 3.5 (2/7); after 2.0 (0/5); p=0.001) and also in control group (VAS before 5.1 (2/8); after 4.0 (2/7); p=0.001), but the reduction was significantly more prominent in therapy group (p=0.004). There was a better quality of life in therapy group (WOMAC before 21.35 (4.2/52.1); after 11.45 (0.0/47.9); p=0.001) and also in control group (WOMAC before 25.00 (5.2/60.4); after 20.83 (3.1/55.2); p=0.001), but the score was significantly better in therapy group (p=0.001). Conclusions: Twelve sessions of low-intensity pulsed US has a benefit effect over pain and quality of life in knee OA patients.
Abstract: Background: Knee osteoarthritis (OA) is a common disease worldwide and causes disability in elderly. Recent studies showed that therapeutic ultrasound (US) can reduced pain in various musculoskeletal disorders. Objective: To determined the effect of low-intensity pulsed US on quality of life and reduction of pain in grade 1 to 3 knee OA. Material a...
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Status of Soil-Transmitted Helminths Infection in Ethiopia
Issue:
Volume 3, Issue 3, May 2015
Pages:
170-176
Received:
15 April 2015
Accepted:
5 May 2015
Published:
19 May 2015
Abstract: Soil-transmitted helminth infections are among the most common infections worldwide and affect the poorest and most deprived communities. The three major soil-transmitted helminths (STHs), i.e., Ascaris lumbricoides, Trichuris trichiura and Necator americanus/Ancylostoma duodenale are among the most widespread parasites worldwide. It is estimated that more than 880 million children are in need of treatment for these parasites globally. Several studies in Ethiopia also revealed that intestinal parasite infections are widely distributed with high prevalence rates. This paper reviews status of soil-transmitted helminths prevalence, their impact on health and measurement now taken to monitor the infection in Ethiopia context.
Abstract: Soil-transmitted helminth infections are among the most common infections worldwide and affect the poorest and most deprived communities. The three major soil-transmitted helminths (STHs), i.e., Ascaris lumbricoides, Trichuris trichiura and Necator americanus/Ancylostoma duodenale are among the most widespread parasites worldwide. It is estimated t...
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Perception of Rural People About Persons with Physical Disability: The Case of Yorogo-Yipala Community
Fiasorgbor A. Doris,
Ayagiyire Theresa
Issue:
Volume 3, Issue 3, May 2015
Pages:
177-182
Received:
16 April 2015
Accepted:
1 May 2015
Published:
21 May 2015
Abstract: Disability is often perceived negatively perhaps due to ignorance and some prevailing socio-cultural beliefs as well as economic factors. The challenges facing people with disabilities (PWDs), therefore, are varied and could be in the form of violation of human rights, poverty, stigma, discrimination and exclusion. Disability is closely associated with poverty and is also a barrier to education, employment, access to public services and social protection. In most cases, disability has been addressed through charitable approaches without the recognition of the rights and participation of persons with disabilities, like other citizens. The study used a mixed method where both qualitative and quantitative techniques were employed. Focus group discussions, semi-structured interviews and observation were employed to collect data. The study participants also demonstrated positive perceptions about disability. This is encouraging, even though the positive perceptions appear not to have been translated into attitudinal change. Most participants appear to have positive attitudes toward disability, and this could reduce stigmatization and discrimination against people with physical disabilities (PWPDs). This is also an indication that stigma and discrimination against the disabled were not widespread among the respondents.
Abstract: Disability is often perceived negatively perhaps due to ignorance and some prevailing socio-cultural beliefs as well as economic factors. The challenges facing people with disabilities (PWDs), therefore, are varied and could be in the form of violation of human rights, poverty, stigma, discrimination and exclusion. Disability is closely associated ...
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Prevalence of Toxoplasmosis in HIV/AIDS Patients in Mettu Karl Hospital
Kasim Mohammed Yesuf,
Zinabu Teka Melese
Issue:
Volume 3, Issue 3, May 2015
Pages:
183-188
Received:
23 April 2015
Accepted:
11 May 2015
Published:
21 May 2015
Abstract: Toxoplasma gondiiis food and waterborne opportunistic pathogen that causes severe disease in immunocompromised patients. It is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. It has been estimated that one-third of the human population is infected with this parasite. A sample of 120 HIV/AIDS patients has been taken from Mettu Karl Hospital. In this study logistic regression is applied for binary response data. To assess whether the model adequately fit to the data different model checking and model diagnostic have been applied. The study indicates that the prevalence of toxoplasmosis for HIV\AIDS patients in the study area was 60%. The analysis shows that some health, economic and risk behavior factors influence exposure of patients to toxoplasmosis. Further, the study shows that the risk factors of Toxoplasmosis are education, marital status, house toilet, tap water and washing hand and raw meat. The factor that influences toxoplasmosis status can be grouped as risk behavior factors (hand washing and raw meat), demographic and health factors (Education, marital status and house toilet) and economic factors (tap water). Under such grouping we can state that patients who are involved in risky behaviors will have higher risk of contracting toxoplasmosis.
Abstract: Toxoplasma gondiiis food and waterborne opportunistic pathogen that causes severe disease in immunocompromised patients. It is caused by an obligatory intracellular protozoon. It causes a wide range of diseases with toxoplasma encephalitis commonly encountered in HIV/AIDS patients. It has been estimated that one-third of the human population is inf...
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Do traditional Birth Attendants (TBAs) Have a Role in the Prevention of Neonatal Tetanus
Jalal-Eddeen Abubakar Saleh,
Abdullahi Hamisu Walla,
Usman Saidu Adamu
Issue:
Volume 3, Issue 3, May 2015
Pages:
189-193
Received:
8 May 2015
Accepted:
15 May 2015
Published:
26 May 2015
Abstract: Background: In spite of the significant achievement of the global NNT elimination campaign and with the deadline set at 2015, NNT is still among the leading causes of death in 25 developing countries. Additionally, the sub-Saharan African region still has the lowest coverage of Antenatal care services and hospital deliveries. Study Design: Retrospective study Methods: Quantitative cross-sectional involving mothers of NNT children using secondary data collected between January 2008 and December 2013 from northeastern Nigeria. Results: The result shows that a significant difference existed between mothers that delivered with the help of TBAs and those that did not; z-statistic (N = 171) = 5.278, p < .001; 95% confidence interval (CI) = 0.235 to 0.371. Conclusion: The Nigerian government should prioritize its activities to give quality training to the TBAs to help in the delivery of pregnant women who reside especially in the rural underserved communities.
Abstract: Background: In spite of the significant achievement of the global NNT elimination campaign and with the deadline set at 2015, NNT is still among the leading causes of death in 25 developing countries. Additionally, the sub-Saharan African region still has the lowest coverage of Antenatal care services and hospital deliveries. Study Design: Retrospe...
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Evaluation of QTc Value and Relation between QTc Interval and Cardiovascular Risk Factors in Obese Children
Esra Akyuz Ozkan,
Hashem E. Khosroshahi,
Halil Ibrahim Serin,
Zeynep Tuba Ozdemir,
Mahmut Kilic,
U. Aliye Gecit,
Meral Ekim
Issue:
Volume 3, Issue 3, May 2015
Pages:
194-197
Received:
11 May 2015
Accepted:
15 May 2015
Published:
26 May 2015
Abstract: Background: Obesity has a risk factor for sudden cardiac death, because of the tendency to develop arrhythmias. Delay in cardiac repolarization is reflected as QTc prolongation on electrocardiogram. The aim of this study was to investigate QTc interval in obese children and assess the relation between cardiac risk factors and QTc interval. Materials and Methods: Forty five obese children whose body mass index (BMI) persentil was > % 95th and eighty seven control group were enrolled in this study. QTc was derived using Bazett’s Formula. Results: Mean QTc value was found significantly longer in obese children (413.89±23.27ms) than control group (398.95±24.28ms) (p= 0,001) and also prolonged QTc frequency was more than six times in obese (% 15.6) than control group (%2.4). BMI, systolic and diastolic BP, total cholesterol, triglyceride, low-density lipoprotein (LDL), fasting glucose, insulin, left ventricular mass (LVM) and carotid intima media thickness (CIMT) were significantly higher and high-density lipoprotein (HDL) levels and HOMA-IR values were lower in obese group compared with the controls. There was no correlation between QTc, metabolic parameters, systolic and diastolic BP, BMI, LVM and CIMT in obese group. Conclusion: QTc prolongation can be seen more common in obese children and may result in sudden death. So obese children must be followed closely regarding QTc interval.
Abstract: Background: Obesity has a risk factor for sudden cardiac death, because of the tendency to develop arrhythmias. Delay in cardiac repolarization is reflected as QTc prolongation on electrocardiogram. The aim of this study was to investigate QTc interval in obese children and assess the relation between cardiac risk factors and QTc interval. Material...
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